A space shuttle in orbit to repair a damaged satellite is forced to return to Earth after NASA loses contact with astronauts Spencer Armacost (Johnny Depp) and Alex Streck for two minutes. Both were outside the spacecraft when the incident occurred. While Armacost seems to be unaffected, Streck has a much harder time recovering from whatever happened to them. Over time, Armacost's wife Jillian (Charlize Theron) begins to note subtle changes in him. Egged on by a former NASA employee, she beings to believe that her husband is something else. She also learns that she is pregnant.

Washington Square Park, Greenwich Village, Manhattan.

5th Avenue and Washington Mews, Manhattan.

Armacost's Apartment, 1 5th Avenue and East 8th Street, Manhattan.

Subway, Broadway (btw Warren Street and Murray Street) Manhattan.