When Howard (Will Smith) a successful New York advertising executive suffers a great tragedy, he retreats from life. While his concerned friends Whit (Edward Norton), Claire (Kate Winslet) and Simon (Michael Pena) try desperately to reconnect with him, he seeks answers from the universe by writing letters to Love, Time and Death. When his notes bring unexpected personal responses, he begins to understand how these constants interlock in a life fully lived and how even the deepest loss can reveal moments of meaning and beauty.

Bergdorf Goodman Store, 754 5th Avenue and West 58th Street, Manhattan.

West 58th Street and 5th Avenue, Manhattan.

Howard's Apartment, 936 West End Avenue and West 106th Street, Manhattan.

West End Avenue and West 106th Street, Manhattan.

Restaurant, 99 Gansevoort Street and Washington Street, Manhattan.

Allison's Home, 575 Park Avenue and East 63rd Street, Manhattan.

(Entrance Only) Agency Office, 270 Lafayette Street and Prince Street, Manhattan.

otsoNY Comments: Though the agency was based at 270 Lafayette Street, this location was only used for the entrance. For the internal shots, the Wieden Kennedy Agency office at 150 Varick Street was used.

Wieden Kennedy Agency, 150 Varick Street and Vandam Street, Manhattan.

Lafayette Street and Prince Street, Manhattan.

otsoNY Comments: The La Mama Experimental Theatre Club takes on the roll of the Hegel Theater.

LaMama Experimental Theatre, 66 East 4th Street (btw Bowery & 2nd Avenue) Manhattan.

Williamsburg Bridge (Delancey Street, Manhattan to Williamsburg, Brooklyn).

Le Pain Quitidien Restaurant, 861 Lexington Avenue and East 65th Street, Manhattan.

Restaurant, 85 10th Avenue and West 15th Street, Manhattan.

25-27 Columbia Place (btw Joralemon Street and State Street) Brooklyn.

Columbia Place (btw Joralemon Street and State Street) Brooklyn.

Marion Hopkinson Park, Chauncey Street and Thomas S. Boyland Street, Brooklyn.

Chauncey Street and Thomas S. Boyland Street, Brooklyn.

Lafayette Street (btw Jersey Street and Prince Street) Manhattan.

Garden of Eden Shop, 162 West 23rd Street (btw 6th & 7th Avenues) Manhattan.

Remedy Diner, 245 East Houston Street and Norfolk Street, Manhattan.

River Deli, 32 Joralemon Street and Columbia Place, Brooklyn.

St. Ann's Warehouse, 45 Water Street (btw New Dock & Old Dock Streets) Brooklyn.

Bleecker Street and Elizabeth Street, Manhattan.

otsoNY Comments: Although the signs on the pillars suggest that the station is Broadway - Lafayette Street, the actual station used was Church Avenue in Brooklyn.

Subway, Church Avenue and 18th Street, Brooklyn.

Subway, Mulberry Street and Bleecker Street, Manhattan.

Bleecker Street and Lafayette Street, Manhattan.

St. Nicholas Avenue (btw West 181st and 182nd Street) Washington Heights.

182nd Street and St. Nicholas Avenue, Washington Heights, Manhattan.

Marymount School, 1026 5th Avenue and East 84th Street, Manhattan.

Simon's Home, 12 East 13th Street (btw University Place & 5th Avenue) Manhattan.

Madeline's Home, 126 State Street (btw Sidney Place and Henry Street) Brooklyn.

Reservoir Bridge, Central Park (West 94th Street) Manhattan.