Alan Johnson (Don Cheadle) has everything he needs to get through life: a good job, a beautiful and loving wife, and their wonderful children. Yet he feels isolated because he finds having a hard-working job and managing a family too much to handle and has no one to talk to about it. Charlie Fineman (Adam Sandler), on the other hand, doesn't have a job or a family. He used to have both until a terrible loss, and the grief caused him to quit his job and isolate himself from everyone around him. As it turns out, Alan and Charlie were roommates in college, and a chance encounter one night rekindles the friendship they shared. But when Charlie's problems become too much to deal with, Alan is determined to help Charlie come out of his emotional abyss.

otsoNY Comments: Notice how the film-makers have switched the building number to show 2254 when in fact the building is 1172 Park Avenue.

Angela Oakhurst Office, 1172 Park Avenue and East 93rd Street, Manhattan.

Webster Hall, 125 East 11th Street and 3rd Avenue, Manhattan.

Grand Central Terminal, 89 East 42nd Street and Park Avenue, Manhattan.

Cinema Village, 22 East 12th Street and 5th Avenue, Manhattan.