During shopping for Christmas, Frank (Robert De Niro) and Molly (Meryl Streep) run into each other. This fleeting short moment will start to change their lives, when they recognize each other months later in the train home and have a good time together. Although both are married and Frank has two little kids, they meet more and more often, their friendship becoming the most precious thing in their lives.

5th Avenue and West 57th Street, Manhattan.

Grand Central Terminal, 89 East 42nd Street and Park Avenue, Manhattan.

Irving Place and East 18th Street, Manhattan.

Rizzoli Bookstore, 712 5th Avenue and East 56th Street, Manhattan.

Trump Tower, 725 5th Avenue and East 56th Street, Manhattan.

Bank Street (btw West 4th Street and Greenwich Avenue) Manhattan.

Frank's Apartment, 31 Bank Street and West 4th Street, Manhattan.

Manhattan Place, East 36th Street and 1st Avenue, Manhattan.